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Controlling Protein Binding Specificity by a Conformational Shift

✍ Scribed by Michielssens, Servaas; Peters, Jan Henning; Ban, David; Pratihar, Supriya; Becker, Stefan; Sabo, Thomas Michael; Giller, Karin; Donghan, Lee; Griesinger, Christian; de Groot, Bert

Book ID
123049033
Publisher
Biophysical Society
Year
2014
Tongue
English
Weight
102 KB
Volume
106
Category
Article
ISSN
0006-3495

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A possible code is suggested that describes a correspondence between amino acid sequences in stereospecific sites of regulatory proteins and nucleotide sequences at the control sites on DNA. Stereospecific sites of regulatory proteins are assumed to contain pairs of antiparallel polypeptide chain se