An amplified NS0 cell line transfected with a vector expressing a humanized monoclonal antibody (MAb) against CD-18 and glutamine synthetase (GS) was cultivated in a 1.5 L fed-batch culture using a serum-free, glutamine-free medium. Concentrated solutions of key nutrient components were fed periodic
Controlling glycation of recombinant antibody in fed-batch cell cultures
β Scribed by Inn H. Yuk; Boyan Zhang; Yi Yang; George Dutina; Kimberly D. Leach; Natarajan Vijayasankaran; Amy Y. Shen; Dana C. Andersen; Bradley R. Snedecor; John C. Joly
- Publisher
- John Wiley and Sons
- Year
- 2011
- Tongue
- English
- Weight
- 483 KB
- Volume
- 108
- Category
- Article
- ISSN
- 0006-3592
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