𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Controlling glycation of recombinant antibody in fed-batch cell cultures

✍ Scribed by Inn H. Yuk; Boyan Zhang; Yi Yang; George Dutina; Kimberly D. Leach; Natarajan Vijayasankaran; Amy Y. Shen; Dana C. Andersen; Bradley R. Snedecor; John C. Joly


Publisher
John Wiley and Sons
Year
2011
Tongue
English
Weight
483 KB
Volume
108
Category
Article
ISSN
0006-3592

No coin nor oath required. For personal study only.


πŸ“œ SIMILAR VOLUMES


Fed-batch culture of recombinant NS0 mye
✍ Weichang Zhou; Chun-Chiang Chen; Barry Buckland; John Aunins πŸ“‚ Article πŸ“… 1997 πŸ› John Wiley and Sons 🌐 English βš– 231 KB πŸ‘ 1 views

An amplified NS0 cell line transfected with a vector expressing a humanized monoclonal antibody (MAb) against CD-18 and glutamine synthetase (GS) was cultivated in a 1.5 L fed-batch culture using a serum-free, glutamine-free medium. Concentrated solutions of key nutrient components were fed periodic

Protein-free fed-batch culture of non-GS
✍ John E. Burky; Mark C. Wesson; Amy Young; Sharyn Farnsworth; Ben Dionne; Ying Zh πŸ“‚ Article πŸ“… 2006 πŸ› John Wiley and Sons 🌐 English βš– 368 KB πŸ‘ 1 views

## Abstract Presented is a novel antibody production platform based on the fed‐batch culture of recombinant, NS0‐derived cell lines. A standardized fed‐batch cell culture process was developed for five non‐GS NS0 cell lines using enriched and optimized protein‐free, cholesterol‐free, and chemically

Fermentative capacity in high-cell-densi
✍ Pim van Hoek; Erik de Hulster; Johannes P. van Dijken; Jack T. Pronk πŸ“‚ Article πŸ“… 2000 πŸ› John Wiley and Sons 🌐 English βš– 106 KB πŸ‘ 2 views

High-cell-density fed-batch processes for bakers' yeast production will involve a low-average-specific growth rate due to the limited oxygen-transfer capacity of industrial bioreactors. The relationship between specific growth rate and fermentative capacity was investigated in aerobic, sucrose-limit

Influence of intracellular nucleotide an
✍ N. Kochanowski; F. Blanchard; R. Cacan; F. Chirat; E. Guedon; A. Marc; J.-L. Goe πŸ“‚ Article πŸ“… 2008 πŸ› John Wiley and Sons 🌐 English βš– 314 KB πŸ‘ 1 views

## Abstract Both the macroheterogeneity of recombinant human IFN‐γ produced by CHO cells and intracellular levels of nucleotides and sugar nucleotides, have been characterized during batch and fed‐batch cultures carried out in different media. Whereas PF‐BDM medium was capable to maintain a high pe