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Controlling cardiac arrhythmias by lengthening repolarization: Historical overview

✍ Scribed by Bramah N. Singh

Book ID
113119189
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
792 KB
Volume
72
Category
Article
ISSN
0002-9149

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Block of I(Kr) is of major concern in drug safety. The objective of this study was to assess prolongation of cardiac repolarization during the combined use of two I(Kr) blockers when administered concomitantly or sequentially. (1) When isolated hearts from male guinea pigs were perfused concomitantl