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Controlling Amyloid-β Peptide(1–42) Oligomerization and Toxicity by Fluorinated Nanoparticles

✍ Scribed by Ana M. Saraiva ; Isabel Cardoso ; M. Carmo Pereira; Manuel A. N. Coelho; Maria João Saraiva; Helmuth Möhwald; Gerald Brezesinski

Book ID
102789570
Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
675 KB
Volume
11
Category
Article
ISSN
1439-4227

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## Abstract The amyloid‐β peptide (Aβ) plays a central role in the mechanism of Alzheimer's disease, being the main constituent of the plaque deposits found in AD brains. Aβ amyloid formation and deposition are due to a conformational switching to a β‐enriched secondary structure. Our strategy to i