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Controlling aggregation propensity in A53T mutant of alpha-synuclein causing Parkinson’s disease

✍ Scribed by Sonu Kumar; Anita Sarkar; Durai Sundar


Book ID
116298885
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
479 KB
Volume
387
Category
Article
ISSN
0006-291X

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## Abstract Monogenic forms of Parkinson's disease (PD) provide an opportunity to examine mechanisms underlying phenotypic variation. Glutathione S‐transferase (GST) has detoxification and antioxidative functions. To screen genetic variations in GST for an effect on the onset age (OA) of PD, we typ