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Controlled release of rhBMP-2 loaded poly(dl-lactic-co-glycolic acid)/calcium phosphate cement composites in vivo

✍ Scribed by P.Q. Ruhé; O.C. Boerman; F.G.M. Russel; P.H.M. Spauwen; A.G. Mikos; J.A. Jansen


Book ID
113690941
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
307 KB
Volume
106
Category
Article
ISSN
0168-3659

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Biocompatibility and degradation of poly
✍ P. Quinten Ruhé; Elizabeth L. Hedberg; Nestor Torio Padron; Paul H. M. Spauwen; 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 English ⚖ 824 KB

## Abstract Injectable calcium phosphate (Ca‐P) cement materials exhibit favorable osteocompatible behavior but are resorbed slowly because of a lack of a bone ingrowth–enabling macroporosity. In this study, poly(DL‐lactic‐__co__‐glycolic acid) (PLGA) microparticles (average size 66 ± 25 μm) were i