Controlled release of nerve growth factor from a heparin-containing fibrin-based cell ingrowth matrix

Release rate controls biological activit

Release rate controls biological activity of nerve growth factor released from fibrin matrices containing affinity-based delivery systems

✍ Matthew D. Wood; Shelly E. Sakiyama-Elbert 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 317 KB 👁 1 views

## Abstract Previously, combinatorial techniques were used to identify peptide sequences exhibiting high, medium, and low affinity for heparin. Bidomain peptides were synthesized containing a transglutaminase sequence for one domain and one of the heparin‐affinity sequences for the other domain. A