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Controlled release of macromolecules from PLA microspheres: using porous structure topology

โœ Scribed by T Ehtezazi; C Washington

Book ID
114160699
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
413 KB
Volume
68
Category
Article
ISSN
0168-3659

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Novel macromolecular therapeutics such as peptides, proteins, and DNA are advancing rapidly toward the clinic. Because of typically low oral bioavailability, macromolecule delivery requires invasive methods such as frequently repeated injections. Parenteral depots including biodegradable polymer mic