The thermal stabilities of supercoiled (SC) and linear/open circular (LIN/ OC) forms of plasmid DNA when complexed with cationic lipids or cationic polymers used for cellular transfection were assessed using differential scanning calorimetry. Differences in the stability of SC DNA produced by the ca
Controlled complexation of plasmid DNA with cationic polymers: Effect of surfactant on the complexation and stability of the complexes
✍ Scribed by Marjukka Ikonen; Lasse Murtomäki; Kyösti Kontturi
- Book ID
- 108099848
- Publisher
- Elsevier Science
- Year
- 2008
- Tongue
- English
- Weight
- 646 KB
- Volume
- 66
- Category
- Article
- ISSN
- 0927-7765
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shi, J a p a n ## Synopsis The interaction between DNA and ionen polymers, -[N+(CH~)Z(CHZ),N+(CH~)~ ( C H Z ) ~] ~-, with rn-n of 3-3,6-6, and 6-10 were examined in order to know how the binding behavior of cationic polymers with DNA depends on the charge density of polycation. The ionen polymer