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Control, responses and modularity of cellular regulatory networks: a control analysis perspective

โœ Scribed by Bruggeman, F.J.; Snoep, J.L.; Westerhoff, H.V.

Book ID
117813234
Publisher
The Institution of Engineering and Technology
Year
2008
Tongue
English
Weight
296 KB
Volume
2
Category
Article
ISSN
1751-8849

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โœ FRANK J. BRUGGEMAN; HANS V. WESTERHOFF; JAN B. HOEK; BORIS N. KHOLODENKO ๐Ÿ“‚ Article ๐Ÿ“… 2002 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 246 KB

The sheer complexity of intracellular regulatory networks, which involve signal transducing, metabolic, and genetic circuits, hampers our ability to carry out a quantitative analysis of their functions. Here, we describe an approach that greatly simplifies this type of analysis by capitalizing on th