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Control of the G1 phase cyclin-dependent kinases by mitogenic growth factors and the extracellular matrix

โœ Scribed by Richard K. Assoian


Book ID
117757820
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
820 KB
Volume
8
Category
Article
ISSN
1359-6101

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## Abstract Transforming growth factor ฮฒ1 (TGFฮฒ1) inhibits epithelial cell proliferation late in the G1 phase of the cell cycle. We examined the effect of TGFฮฒ1 on known late G1 cell cycle regulators in an attempt to determine the molecular mechanism of growth inhibition by this physiological inhib