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Control of the blood–polymer interface by plasma treatment

✍ Scribed by Nicoleta Dumitrascu; Catalin Borcia; Gabriela Borcia


Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
177 KB
Volume
87B
Category
Article
ISSN
1552-4973

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✦ Synopsis


Abstract

Plasma that is generated using dielectric barrier discharge is used to modify the surface properties of polymers used in medicine, at atmospheric pressure. Treatments are performed on films of polyamide‐6, high density polyethylene, polymethylmetacrylate, and polytetrafluorethylene, selected for their medical applications. The plasma treatment conditions are discussed, in relation with relevant parameters for the adhesion properties, like the surface energy components, interfacial tension, surface topography, structural changes, and chemical composition. The interface properties are analyzed using the most important fluids implicated in the interfacial events related to the coagulation process at the interface of blood–polymer surface, respectively, water, whole blood, fibrinogen, and albumin. The physical and chemical modification of the surface is theoretically favorable to the interaction of the polymer with the blood and its components, by means of interfacial tension reduction, polarity increase, cleaning, ordering of molecular chains, functionalization, and stabilization effects. © 2008 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater 2008


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