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Control of Spasticity in a Multiple Sclerosis Model is mediated by CB1, not CB2, Cannabinoid Receptors

✍ Scribed by G Pryce; D Baker


Book ID
110009391
Publisher
Nature Publishing Group
Year
2009
Tongue
English
Weight
110 KB
Volume
150
Category
Article
ISSN
0007-1188

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Cannabinoids regulate numerous physiological and pathological events like inflammation or neurodegeneration via CB(1) and CB(2) receptors. The mechanisms behind cannabinoid effects show a high variability and may also involve transient receptor potential channels (TRP) and N-type voltage-gated Ca(2+