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Control of Replication Timing by a Transcriptional Silencer

✍ Scribed by David C Zappulla; Rolf Sternglanz; Janet Leatherwood


Book ID
114319195
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
414 KB
Volume
12
Category
Article
ISSN
0960-9822

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We previously showed that the V-J intervening sequence of the chicken lambda immunoglobulin locus contains a strong silencer that acts both on transcription and rearrangement. We show here that the transcriptional silencer activity can be ascribed to a minimal 150-bp fragment. The rearrangement sile