Control of peptide conformation by the Thorpe-Ingold effect (Cα-tetrasubstitution)
✍ Scribed by Claudio Toniolo; Marco Crisma; Fernando Formaggio; Cristina Peggion
- Book ID
- 102672447
- Publisher
- Wiley (John Wiley & Sons)
- Year
- 2001
- Tongue
- English
- Weight
- 521 KB
- Volume
- 60
- Category
- Article
- ISSN
- 0006-3525
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The preferred conformations of C"-methyl phenylglycine, C"-methyl phenylalanine, and C"-methyl homophenylalanine residues, as determined in model peptides (including homopeptides) by Fourier transform ir absorption, 'H-nmr, CD, and x-ray diffraction techniques, are compared with the aim of investiga
## Abstract The preferred conformation of five, terminally protected, model peptide series to the hexamer level, based on three novel crowned, C^α^‐methyl L‐DOPA amino acids combined with either L‐Ala/Aib or Gly/Aib, were assessed in structure supporting solvents using FT‐IR absorption, ^1^H NMR, a