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Control of pepsinogen synthesis and secretion in primary monolayer cultures of canine gastric chief cells

โœ Scribed by J. Defize; R. H. Hunt


Book ID
112557965
Publisher
Springer US
Year
1988
Tongue
English
Weight
795 KB
Volume
33
Category
Article
ISSN
0163-2116

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Expression and phosphorylation of a MARC
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In gastric chief cells, agents that activate protein kinase C (PKC) stimulate pepsinogen secretion and phosphorylation of an acidic 72-kDa protein. The isoelectric point and molecular mass of this protein are similar to those for a common PKC substrate; the MARCKS (for Myristoylated Alanine-Rich C K