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Control of glycosylation of MHC class II-associated invariant chain by translocon-associated RAMP4

✍ Scribed by Schroder, K.


Book ID
119770418
Publisher
Nature Publishing Group
Year
1999
Tongue
English
Weight
448 KB
Volume
18
Category
Article
ISSN
0261-4189

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MHC class II-associated invariant chain
✍ Georg Malcherek; Christoph Wirblich; Nicholas Willcox; Hans-Georg Rammensee; Joh πŸ“‚ Article πŸ“… 1998 πŸ› John Wiley and Sons 🌐 English βš– 198 KB

Proteolysis of the invariant chain (li) leads to the generation of abundant MHC class II-associated invariant chain peptides (CLIP), which bind in the MHC class II binding groove via supermotifs in a manner similar to that of antigenic peptides. We have engineered an li vector with the capacity to e