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Control of early thymocyte development by the pre-T cell receptor complex: A receptor without a ligand?

✍ Scribed by David L. Wiest; Michael Carleton


Book ID
115647980
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
408 KB
Volume
11
Category
Article
ISSN
1044-5323

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The sensitivity of immature thymocytes to antigen-induced deletion has been shown to correlate with their differentiation status. By using an in vitro approach we have investigated whether parameters of antigenic stimulation may also affect the response of thymocytes. Two T cell receptor (TcR)-trans