𝔖 Bobbio Scriptorium
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Control of CD4+ T-cell memory by cytokines and costimulators

✍ Scribed by Hans Dooms; Abul K. Abbas

Book ID
110746649
Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
895 KB
Volume
211
Category
Article
ISSN
0105-2896

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## Abstract The T cell surface protein CD28 provides a critical costimulatory signal for T cell activation. With age, humans accumulate increasing numbers of CD28^–^ T cells, and this loss of CD28 expression is exacerbated certain disease states, such as HIV infection, autoimmune conditions or canc