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Control of Ca2+ Release by Action Potential Configuration in Normal and Failing Murine Cardiomyocytes

✍ Scribed by Louch, William E.; Hake, Johan; Jølle, Guro Five; Mørk, Halvor K.; Sjaastad, Ivar; Lines, Glenn T.; Sejersted, Ole M.

Book ID: 119207419
Publisher: Biophysical Society
Year: 2010
Tongue: English
Weight: 924 KB
Volume: 99
Category: Article
ISSN: 0006-3495
DOI: 10.1016/j.bpj.2010.06.055

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## Summary The action potential (AP) in __Chara__ is associated with a transient elevation in the concentration of cytoplasmic‐free Ca^2+^ ([Ca^2+^]~cyt~). The quenching properties of the fluorescent Ca^2+^ indicator dye fura‐dextran, in combination with Mn^2+^, was used to investigate whether this