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Control elements in the asymmetric tandem alkylation of α-alkylidene-γ-butyrolactone derivatives

✍ Scribed by Kiyoshi Tomioka; Hisashi Kawasaki; Kenji Koga

Book ID
104228760
Publisher
Elsevier Science
Year
1985
Tongue
French
Weight
237 KB
Volume
26
Category
Article
ISSN
0040-4039

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✦ Synopsis

Control elements in the highly selective construction of contiguous tertiary and quaternary carbon centers by the tandem alkylation of a-alkylidene-y-butyrolactone derivatives were studied.

It is clarified that the stereochemical course of the reaction is rationalized by evaluating highly selective 1,2-, 1,3-, and 1,4-asymmetric inductions.

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