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Contributions of the Ionizable Amino Acids to the Stability of Staphylococcal Nuclease †

✍ Scribed by Meeker, Alan K.; Garcia-Moreno E., Bertrand; Shortle, David

Book ID
126782026
Publisher
American Chemical Society
Year
1996
Tongue
English
Weight
420 KB
Volume
35
Category
Article
ISSN
0006-2960

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📜 SIMILAR VOLUMES

Accommodation of single amino acid inser
Accommodation of single amino acid insertions by the native state of staphylococcal nuclease
✍ John Sondek; David Shortle 📂 Article 📅 1990 🏛 John Wiley and Sons 🌐 English ⚖ 629 KB

## Abstract Single alanine and glycine insertions were introduced at 20 randomly selected positions in staphylococcal nuclease. The resulting changes in catalytic activity and in stability to guanidine hydrochloride denaturation indicate that the native state structure is frequently able to accommo