Recent progress in experimental mouse embryology has provided new approaches to the genetic manipulation of the mammalian embryo. The production of uniparental embryos enables one to compare maternal and paternal gene activity during development, to study the biological consequences of homozygosity
Contributions of mammalian embryo transfer to developmental genetics
โ Scribed by Kraemer, Duane C. ;Opitz, John M. ;Renolds, James F.
- Publisher
- John Wiley and Sons
- Year
- 1984
- Tongue
- English
- Weight
- 444 KB
- Volume
- 18
- Category
- Article
- ISSN
- 0148-7299
No coin nor oath required. For personal study only.
โฆ Synopsis
The process of transferring preimplantation embryos from the reproductive tract of one female to that of another, commonly referred to as embryo transfer (ET), has been used extensively for exploration of basic mechanisms of developmental genetics. ET has also permitted practical application of such basic knowledge to selective breeding of livestock and treatment of infertility. Contributions of mammalian embryo transfer are presented as they pertain to studies of heredity vs environment, gamete maturation, fertilization, differentiation, and genetic transformation. Future applications of embryo transfer to the study of developmental genetics are likely to include extensive use of microsurgical techniques on a wide variety of mammalian embryos.
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