Contributions of internal motions to molecular dynamics in solution. A nuclear magnetic resonance investigation

✍ Scribed by Claudio Rossi

• Publisher: Elsevier Science
• Year: 1992
• Tongue: English
• Weight: 312 KB
• Volume: 193
• Category: Article
• ISSN: 0009-2614
• DOI: 10.1016/0009-2614(92)85847-4

✦ Synopsis

The dynamical properties of piroxicam in solution were investigated on the basis of carbon spin-lattice relaxation data. In order to account for the complex molecular motion, an analysis based on Woessner's equation is proposed. Correlation times describing overall reorientation and internal motions were determined. Our results demonstrate the existence of a unique molecular axis for internal reorientation, and enable geometrical correlations based on the calculated effective correlation times to be defined.