Contribution of transmission electron microscopy to fine-needle aspiration biopsy diagnosis: Comparison of cytology and combined cytology and transmission electron microscopy with final histological diagnosis
✍ Scribed by Guillermo E. Quinonez; Esther Ravinsky; Maria Paraskevas; Elaine Kutryk; Luis G. Quinonez
- Publisher
- John Wiley and Sons
- Year
- 1996
- Tongue
- English
- Weight
- 781 KB
- Volume
- 15
- Category
- Article
- ISSN
- 8755-1039
No coin nor oath required. For personal study only.
✦ Synopsis
This repon evaluates 74fine-needle aspiration biopsies processed for transmission electron microscopy with subsequent surgical procedure. The specijicity of diagnosis obtained by cytology alone was compared to that obtained by cytology and electron microscopy. using histologic diagnosis as the gold standard. When cytology gave a diagnosis of malignancy but could not give tumor cateRory or type, electron microscopy could correctly give both. When cytology could give tumor category but not type, electron microscopy correctly ident$ed type in the majority of cases. When cytology gave tumor category and type, electron microscopv confirmed the diagnosis. Transmission electron microscopy is very helpful when the C.V- topthologist can diagnose ma1igmnc.v but cannot give tumor category a d o r type. When the cvtopathologist is specific in hisher diagnosis, TEM is not as helpful. Diagn Cytopathol 1996;lS: 282-287. o 19% WII~Y-LISS. IN