Contribution of the H- and L-chains and of the binding site to the idiotypic specificities of mouse anti-GAT antibodies
✍ Scribed by Gérard Sommé; JoséRocca Serra; Lise Leclercq; Jean-Louis Moreau; Jean-Claude Mazie; Danielle Moinier; Michel Fougereau; Jacques Thèze
- Book ID
- 119089149
- Publisher
- Elsevier Science
- Year
- 1982
- Tongue
- English
- Weight
- 907 KB
- Volume
- 19
- Category
- Article
- ISSN
- 0161-5890
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📜 SIMILAR VOLUMES
## Abstract Three types of idiotypic specificities compose the major idiotype of anti‐poly (L‐Glu^60^‐L‐Ala^30^‐L‐Tyr^10^) (GAT) antibodies from BALB/c mice (idiotype termed GAT‐715). Assays have been designed to analyze and study the distribution of these specificities. The highly conserved idioty
## Abstract Seventeen hybridomas, secreting monoclonal anti‐idiotypic antibodies (IDA) directed against the BALB/c ABPC48 idiotype, were isolated from one immunized BALB/c mouse. Several IDA also bind another BALB/c idiotype: UPC10. ABPC48 and UPC10 are both myeloma proteins with a β(2→6)‐polyfruct