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Contribution of the C1A and C1B Domains to the Membrane Interaction of Protein Kinase C †

✍ Scribed by Giorgione, Jennifer; Hysell, Michelle; Harvey, Daniel F.; Newton, Alexandra C.


Book ID
126057613
Publisher
American Chemical Society
Year
2003
Tongue
English
Weight
202 KB
Volume
42
Category
Article
ISSN
0006-2960

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Taxonomy and function of C1 protein kina
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C1 domains are compact alpha/beta structural units of about 50 amino acids which tightly bind two zinc ions. These domains were first discovered as the loci of phorbol ester and diacylglycerol binding to conventional protein kinase C isozymes, which contain 2 C1 domains (C1A and C1B) in their N-term