Contribution of Response Surface Design to the Synthesis of Monoacylglycerols Catalyzed by Rhizopus sp. lipase

Response surface methodology as a tool t

Response surface methodology as a tool to study the lipase-catalyzed synthesis of betulinic acid ester

✍ Yamin Yasin; Mahiran Basri; Faujan Ahmad; Abu Bakar Salleh 📂 Article 📅 2008 🏛 Wiley (John Wiley & Sons) 🌐 English ⚖ 188 KB

## Abstract **BACKGROUND:** The synthesis of betulinic acid ester using betulinic acid and oleyl alcohol catalyzed by Novozym 435 (immobilized __Candida antarctica__ lipase) was carried out. Response surface methodology (RSM) based on a five‐level, three‐variable, central composite rotatable design