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Contribution of p53-mediated Bax transactivation in theaflavin-induced mammary epithelial carcinoma cell apoptosis

✍ Scribed by Lakshmishri Lahiry; Baisakhi Saha; Juni Chakraborty; Sankar Bhattacharyya; Sreya Chattopadhyay; Shuvomoy Banerjee; Tathagata Choudhuri; Debaprasad Mandal; Arindam Bhattacharyya; Gaurisankar Sa; Tanya Das

Publisher
Springer
Year
2008
Tongue
English
Weight
597 KB
Volume
13
Category
Article
ISSN
1360-8185

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## Abstract Recent studies have shown that MEK/ERK‐mediated signals play a major role in regulation of activity of p53 tumor suppressor protein. In this study, we investigated whether or not there is functional interaction between p53 and MEK/ERK pathways in epithelial breast cancer cells exposed t