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Contribution of Methylenetetrahydrofolate Reductase (MTHFR) Polymorphisms to Negative Symptoms in Schizophrenia

✍ Scribed by Joshua L. Roffman; Anthony P. Weiss; Shaun Purcell; Christopher A. Caffalette; Oliver Freudenreich; David C. Henderson; Teodoro Bottiglieri; Donna H. Wong; Charles H. Halsted; Donald C. Goff

Book ID
119197518
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
202 KB
Volume
63
Category
Article
ISSN
0006-3223

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## Abstract Different lines of evidence indicate that methylenetetrahydrofolate reductase (__MTHFR__) functional gene polymorphisms, causative in aberrant folate–homocysteine metabolism, are associated with increased vulnerability to several heritable developmental disorders. Opposing views are exp