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Contribution of Hydrophobicity to Thermodynamics of Ligand-DNA Binding and DNA Collapse

✍ Scribed by Patel, Mayank M.; Anchordoquy, Thomas J.


Book ID
119919091
Publisher
Biophysical Society
Year
2005
Tongue
English
Weight
572 KB
Volume
88
Category
Article
ISSN
0006-3495

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## Abstract The method of solution of the nonlinear Poisson–Boltzmann equation was used to calculate electrostatic energy of binding of various aromatic ligands with DNA oligomers of different length. Analysis of the electrostatic contribution was made in terms of a two‐step DNA binding process: fo