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Contribution of genetic variation within SuprMam1 and SuprMam2 to breast cancer susceptibility

✍ Scribed by M Ratnadiwakara; M Rooke; R Williams; AC Blackburn


Book ID
115027851
Publisher
BioMed Central
Year
2012
Tongue
English
Weight
81 KB
Volume
10
Category
Article
ISSN
1897-4287

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## Abstract Germline mutations in the tumor suppressor gene __TP53__ are associated with high incidence of early‐onset malignancies, and somatic mutations occur in 20–40% of all breast cancer cases. We investigated the association of common genetic variation in __TP53__ and its flanking genes, __WD