Contribution of electrostatic and hydrophobic interactions to the adsorption of proteins by aluminium-containing adjuvants
β Scribed by Ragheb H. Al-Shakhshir; Fred E. Regnier; Joe L. White; Stanley L. Hem
- Book ID
- 116116921
- Publisher
- Elsevier Science
- Year
- 1995
- Tongue
- English
- Weight
- 421 KB
- Volume
- 13
- Category
- Article
- ISSN
- 0264-410X
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## Abstract The adsorption equilibria of bovine serum albumin (BSA), Ξ³βglobulin, and lysozyme to three kinds of Cibacron blue 3GA (CB)βmodified agarose gels, 6% agarose gelβcoated steel heads (6AS), Sepharose CLβ6B, and a homeβmade 4% agarose gel (4AB), were studied. We show that ionic strength has
## NOTE Electrostatic Contribution to the Energy and Entropy of Protein Adsorption and proton dissociation. In addition, van der Waals (primarily dispersion) interactions may play a role (4). ## Protein adsorption is complicated by the many contributions to We focus here on electrostatics, whic