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Contribution of antioxidants to preventive effect of mesna in cyclophosphamide-induced hemorrhagic cystitis in rats

✍ Scribed by Ibrahim Yildirim; Ahmet Korkmaz; Sukru Oter; Ayhan Ozcan; Emin Oztas

Publisher
Springer
Year
2004
Tongue
English
Weight
316 KB
Volume
54
Category
Article
ISSN
0344-5704

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πŸ“œ SIMILAR VOLUMES

Efficacy of mesna in preventing further
Efficacy of mesna in preventing further cyclophosphamide-lnduced hemorrhagic cystitis
✍ Luce, James K. ;Simons, Jarid A. πŸ“‚ Article πŸ“… 1988 πŸ› John Wiley and Sons 🌐 English βš– 217 KB

Mesna is a sulfhydryl compound that reacts with the metabolites of cyclophosphamide that are excreted in the urine and may produce bladder wall irritation. Mesna is converted in the blood to a biochemically inactive compound that is reduced back to mesna in the kidneys. In this way it has the potent