Selective inhibition of activin receptor
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Yasuji Mori; Wataru Ishida; Swati Bhattacharyya; Yongzhong Li; Leonidas C. Plata
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Article
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2004
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John Wiley and Sons
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English
⚖ 957 KB
## Abstract ## Objective Members of the transforming growth factor β (TGFβ) cytokine superfamily play critical roles in both homeostasis and disease. In light of their profibrotic effects, these molecules are implicated in the pathogenesis of fibrosis. In fibroblasts, TGFβ signals through the acti