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Contrasting steric effects of the ketones and aldehydes in the reactions of the diisopinocampheyl enolborinates of methyl ketones with aldehydes

✍ Scribed by P.Veeraraghavan Ramachandran; Wei-chu Xu; Herbert C. Brown


Publisher
Elsevier Science
Year
1996
Tongue
French
Weight
268 KB
Volume
37
Category
Article
ISSN
0040-4039

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Steric Effects in the Reduction of Keton
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## Abstract The rates for the reduction of ketones with sodium borohydride are interpreted in terms of two parameters, both derived from force‐field calculations; __i.e.__ the strain difference between alcohol and ketone (Ξ” strain) and the steric hindrance towards approach of the hydride R. Models