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Contrasting Genetic Influence of CCR2 and CCR5 Variants on HIV-1 Infection and Disease Progression

โœ Scribed by Smith, M. W.

Book ID
121158238
Publisher
American Association for the Advancement of Science
Year
1997
Tongue
English
Weight
582 KB
Volume
277
Category
Article
ISSN
0036-8075

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## Abstract Homozygous (ฮ”ccr5/ฮ”ccr5) and heterozygous (CCR5/ฮ”ccr5) deletions in the ฮฒโ€chemokine receptor 5 (CCR5) gene, which encodes for the major coโ€receptor for macrophageโ€tropic HIVโ€1 entry, have been implicated in resistance to HIV infection and in protection against disease progression, respe