Contrasting effects of suspension on hind limb muscles in the hamster
β Scribed by Kristine Corley; Nancy Kowalchuk; Alan J. McComas
- Book ID
- 115897770
- Publisher
- Elsevier Science
- Year
- 1984
- Tongue
- English
- Weight
- 669 KB
- Volume
- 85
- Category
- Article
- ISSN
- 0014-4886
No coin nor oath required. For personal study only.
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## Abstract The hamster has been the accepted model of emphysema since the 1970s, demonstrating diseaseβrelated effects on respiratory skeletal muscle. However, there is scant information available about the model's ability to replicate the peripheral skeletal muscle changes seen in human disease,
Dorsiflexion of one unloaded hind limb caused hypertrophy of the soleus relative to weight-bearing controls and faster growth of the plantaris and gastrocnemius muscles relative to the contralateral freely moving muscles. Unloading of the soleus muscle diminished primarily myofibrillar proteins wher