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Contrasting effects of excitotoxic lesions of the prefrontal cortex on the behavioural response to d-amphetamine and presynaptic and postsynaptic measures of striatal dopamine function in monkeys

✍ Scribed by L.S Wilkinson; R Dias; K.L Thomas; S.J Augood; B.J Everitt; T.W Robbins; A.C Roberts


Book ID
117491847
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
242 KB
Volume
80
Category
Article
ISSN
0306-4522

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The present experiments assessed the acute and delayed effects of D-1 dopamine (DA) receptor blockade in the medial prefrontal cortex (mPFC) on pre-and postsynaptic indices of DA neurotransmission in the nucleus accumbens (N.Acc). Different groups of rats received intra-mPFC injections of saline (co