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Contrasting Effects of Cyclosporine and Rapamycin in De Novo Generation of Alloantigen-Specific Regulatory T Cells

✍ Scribed by W. Gao; Y. Lu; B. El Essawy; M. Oukka; V. K. Kuchroo; T. B. Strom


Book ID
114804414
Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
406 KB
Volume
7
Category
Article
ISSN
1600-6135

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## CD4Ψ‰CD25Ψ‰ regulatory T cells (T-regs ) are central to the maintenance of immune tolerance and represent an immune intervention candidate in autoimmune hepatitis (AIH), a condition characterized by impaired T-reg number and function. We investigated whether T-regs can be expanded from the existi