Early stages investigation of USPIO-induced signal loss after focal cerebral ischemia in mice J. Marsh: Potential of streptokinase-activated nanoparticles for early revascularization in acute ischemic stroke P. Caravan: Molecular MR imaging of myocardial collagen and assessment of myocardial perfusion E. Canet-Soulas: In-vivo USPIOs follow-up and optimized MRI protocol for inflammation imaging in atherosclerotic plaques C. Corot: MMP-targeted Gd chelate for atherosclerotic imaging: experimental proof of concept Y. Ni: Necrosis avid contrast agents: evidence in favor of hypothetical mechanisms and new potential applications SESSION 2: MICROVASCULAR AND LYMPHATIC IMAGING Moderators: R. Brasch, R. Pollard
C. Cuenod: Unified theory of pharmacokinetic modeling for measuring the microvascular parameters using DCE-MRI and DCE-CT R. Brasch: Characterizing cancer microvasculature: correlations of dynamic macromolecular contrast media-enhanced MRI with microscopic morphology L. Fournier: Can clinical DCE-CT using small molecular iodinated contrast agent detect and quantify the effect of anti-angiogenic drugs on metastatic renal cell carcinoma? B. Yeh: Novel macromolecular iodinated contrast medium permits assays of cancer microvascular leakiness in response to anti-VEGF antibody using dynamic CT D. R. Vera: Lymphoseek: a molecular imaging agent for sentinel node mapping of melanoma, breast and gastrointestinal cancers H. Kobayashi: A multi-modal and multi-color dendrimer-based nano-sized contrast agent for near-infrared optical and radionuclide lymphatic imaging