## Abstract The enhancement properties of gadobutrol (40 and 80 μmol/kg body weight, 550 daltons), gadolinium‐DTPA‐polylysine (20 μmol/kg body weight, 53,000 daltons) and gadolinium‐DTPA‐cascade‐polymer (20 μmol/kg body weight, < 30,000 Daltons) were investigated in abdominal MR imaging using a pig
Contrast enhancement of the gastrointestinal tract on MR images using intravenous gadolinium-DTPA
✍ Scribed by Mirowitz, Scott A.
- Publisher
- Springer-Verlag
- Year
- 1993
- Tongue
- English
- Weight
- 846 KB
- Volume
- 18
- Category
- Article
- ISSN
- 2366-004X
No coin nor oath required. For personal study only.
✦ Synopsis
Gadopentetate dimeglumine was administered intravenously to 16 patients undergoing abdominal magnetic resonance (MR) imaging. Tl-weighted and fat-suppressed Tl-weighted images were acquired before and after intravenous administration of 0.1 mmol/kg gadopentetate dimeglumine. The stomach, small bowel, and colon were analyzed regarding the presence and relative intensity of contrast enhancement. Diffuse enhancement of the gastrointestinal tract wall was observed in all patients following contrast material administration. Such enhancement was most conspicuous on fat-suppressed T1weighted images. Quantitative measurements indicated that the wall of the gastrointestinal tract enhanced approximately 100% with gadopentetate dimeglumine. This study demonstrates that enhancement of the normal gastrointestinal tract occurs routinely when intravenous gadopentetate dimeglumine is administered, and such enhancement should not be considered indicative of gastrointestinal pathology. Furthermore, it suggests the potential utility for using intravenous rather than orally administered contrast agents to provide enhancement of the gastrointestinal tract on MR images.
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