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Contractile effect of endothelin on isolated iris sphincter muscle of the pig

✍ Scribed by Pierangelo Geppetti; Riccardo Patacchini; Stefania Meini; Stefano Manzini


Book ID
115882666
Publisher
Elsevier Science
Year
1989
Tongue
English
Weight
198 KB
Volume
168
Category
Article
ISSN
0014-2999

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✍ Ryo Suzuki; H. Yoshino; Shunsaku Kobayashi πŸ“‚ Article πŸ“… 1988 πŸ› Springer-Verlag 🌐 English βš– 402 KB

We investigated the effect of pilocarpine on the bovine iris sphincter. This muscle contracted in a dose-dependent manner from 2 x 10(-6) M, with a maximal response at 3 x 10(-3) M. The ED50 values was (1.6 +/- 0.3) x 10(-4) M. Pilocarpine generated a desensitization while desensitization was not si