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Contractile and mitochondrial dysfunction in heart trabeculae from diabetic rats

โœ Scribed by Niraj Bhatt; Miguel A. Aon; Xiaoxu Shen; Brian O'Rourke; Weidong Gao; Sonia Cortassa

Book ID
119327049
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
61 KB
Volume
12
Category
Article
ISSN
1567-7249

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## Abstract In order to evaluate the manner by which fumarate enhances contractility in the anaerobic heart, we examined Ca^++^ movements in isolated heart mitochondria and in the isolated perfused heart. Our experiments showed that in isolated antimycin A plus cyanide treated mitochondria: (a) Ca^