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Continuous sorption of d-cycloserine in a countercurrent of liquid and solid phases

โœ Scribed by L. M. Klyueva; T. V. Torganova

Book ID
112397800
Publisher
Springer
Year
1970
Tongue
English
Weight
483 KB
Volume
4
Category
Article
ISSN
0091-150X

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Combinatorial chemistry of natural produ
Combinatorial chemistry of natural products: Solid phase synthesis of D- and L-cycloserine derivatives
โœ Mikhail F. Gordeev; Gary W. Luehr; Hon C. Hui; Eric M. Gordon; Dinesh V. Patel ๐Ÿ“‚ Article ๐Ÿ“… 1998 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 726 KB

An efficient methodology for a solid phase synthesis of D-and L-cycloserine derivatives is described. Fmoc-D-cycloserine 4 and its L-enantiomer 5 prepared by a selective amine acylation of bis-silylated parent compounds are immobilized on Sasrin or 2-chlorotrityl linker resins using Mitsunobu-type r