Continuous monitoring of urea in blood during dialysis

✍ Scribed by Panote Thavarungkul; Håkan Håkanson; Olle Holst; Bo Mattiasson

• Publisher: Elsevier Science
• Year: 1991
• Tongue: English
• Weight: 447 KB
• Volume: 6
• Category: Article
• ISSN: 0956-5663
• DOI: 10.1016/0956-5663(91)87033-8

✦ Synopsis

Urease was immobilized to porous glass and used in combination with a conductivity meter for determining urea in standard solutions as well as in blood from a patient undergoing dialysis. The sampling unit involves a possibility for heparinization at the sampling point and a dialysis step prior to exposure to the enzyme column. The unit operates in a linear mode in the concentration range 5-50 mM. Monitoring of dialysis process gave good correlation with off-line analyses.