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Continuous intrajejunal infusion of levodopa-carbidopa intestinal gel for patients with advanced Parkinson's disease: a randomised, controlled, double-blind, double-dummy study

✍ Scribed by Olanow, C Warren; Kieburtz, Karl; Odin, Per; Espay, Alberto J; Standaert, David G; Fernandez, Hubert H; Vanagunas, Arvydas; Othman, Ahmed A; Widnell, Katherine L; Robieson, Weining Z; Pritchett, Yili; Chatamra, Krai; Benesh, Janet; Lenz, Robert A; Antonini, Angelo

Book ID
121466253
Publisher
The Lancet
Year
2014
Tongue
English
Weight
309 KB
Volume
13
Category
Article
ISSN
1474-4465

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## Background: Human retinal pigment epithelial (rpe) cells produce levodopa and their transplantation into the striatum might improve continuity of administration compared with that achieved with oral levodopa. we aimed to assess the safety, tolerability, and efficacy of transplantation of microca