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Continuous inhibition of DNA synthesis in mouse ear epidermis using hydroxyurea

โœ Scribed by R.M. Singer; S. Gelfant

Book ID
118875967
Publisher
Elsevier Science
Year
1972
Tongue
English
Weight
169 KB
Volume
73
Category
Article
ISSN
0014-4827

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Hydroxyurea (HU) inhibits the premeiotic DNA replication and the meiotic events that followed, namely readiness, recombination commitment, haploidisation, sporulation commitment and ascus formation. Short incubations with HU (2-4 hrs) during the premeiotic replication (i.e. starting between 3 and 6.