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Continuous delivery of ropinirole reverses motor deficits without dyskinesia induction in MPTP-treated common marmosets

✍ Scribed by K.A. Stockwell; D.J. Virley; M. Perren; M.M. Iravani; M.J. Jackson; S. Rose; P. Jenner

Book ID: 116459303
Publisher: Elsevier Science
Year: 2008
Tongue: English
Weight: 448 KB
Volume: 211
Category: Article
ISSN: 0014-4886
DOI: 10.1016/j.expneurol.2008.01.019

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## Abstract Long‐acting full dopamine D~2~ agonists produce less dyskinesia in 1‐methyl‐4‐phenyl‐1,2,3,6‐tetrahydropyridine (MPTP)‐treated primates and in Parkinson's disease than effective antiparkinsonian doses of levodopa. They do not however, prevent priming for dyskinesia expression on subsequ