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Continuous C-peptide loss in patients with type 1 diabetes and multiethnic background

✍ Scribed by Dantas, Joana R.; Almeida, Mirella H.; Barone, Bianca; Serfaty, Fabiano; Raggio, Luis R.; Kupfer, Rosane; Zajdenverg, Lenita; Oliveira, José E.P.; Rodacki, Melanie

Book ID
122489341
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
172 KB
Volume
99
Category
Article
ISSN
0168-8227

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## Abstract ## Background Type 1 diabetes results from a T‐cell mediated autoimmune destruction of insulin‐producing pancreatic beta‐cells. The 60‐kDa heat‐shock protein (hsp60) is one of the known target self‐antigens. An immunogenic peptide from hsp60, p277, arrested beta‐cell destruction and ma